Ovarian function following intra-ovarian injection of platelet rich plasma in premature ovarian aging

Background: Premature ovarian aging as evidenced by AMH levels less than 0.5 ng/ml is predictive of reduced success in management infertility. The most effective treatment vitro fertilization which not affordable or acceptable to our patients with low socioeconomic background. Intra-ovarian injection autologous platelet rich plasma (PRP) improves the reserve markers but it remains be seen whether pregnancy rate.Methods: This was a prospective study 29 poor (age between 30-40 years, AMH<0.5 ng/ml), AFC<4 both ovaries) who received intra plasma. were followed up for one year and data collected about clinically relevant outcomes like pregnancy.Results: Four women (13.8%) had pregnancy, 3 spontaneous following stimulation intrauterine insemination. All diagnosed clinical two live birth.Conclusions: Given 13.8% rate within we can speculate that PRP may reasonable alternative diminished reserve.